Ontology highlight
ABSTRACT:
SUBMITTER: Phan KL
PROVIDER: S-EPMC2657360 | biostudies-other | 2008 Mar
REPOSITORIES: biostudies-other
The Journal of neuroscience : the official journal of the Society for Neuroscience 20080301 10
The cannabinoid (CB) system is a key neurochemical mediator of anxiety and fear learning in both animals and humans. The anxiolytic effects of delta(9)-tetrahydrocannabinol (THC), the primary psychoactive ingredient in cannabis, are believed to be mediated through direct and selective agonism of CB(1) receptors localized within the basolateral amygdala, a critical brain region for threat perception. However, little is known about the effects of THC on amygdala reactivity in humans. We used funct ...[more]