Ontology highlight
ABSTRACT:
SUBMITTER: Allen M
PROVIDER: S-EPMC4807909 | biostudies-literature | 2015 Aug
REPOSITORIES: biostudies-literature
Allen Mariet M Kachadoorian Michaela M Carrasquillo Minerva M MM Karhade Aditya A Manly Lester L Burgess Jeremy D JD Wang Chen C Serie Daniel D Wang Xue X Siuda Joanna J Zou Fanggeng F Chai High Seng HS Younkin Curtis C Crook Julia J Medway Christopher C Nguyen Thuy T Ma Li L Malphrus Kimberly K Lincoln Sarah S Petersen Ronald C RC Graff-Radford Neill R NR Asmann Yan W YW Dickson Dennis W DW Younkin Steven G SG Ertekin-Taner Nilüfer N
Neurology. Genetics 20150723 2
<h4>Objective</h4>To investigate the top late-onset Alzheimer disease (LOAD) risk loci detected or confirmed by the International Genomics of Alzheimer's Project for association with brain gene expression levels to identify variants that influence Alzheimer disease (AD) risk through gene expression regulation.<h4>Methods</h4>Expression levels from the cerebellum (CER) and temporal cortex (TCX) were obtained using Illumina whole-genome cDNA-mediated annealing, selection, extension, and ligation a ...[more]