Ontology highlight
ABSTRACT:
SUBMITTER: Jeng MY
PROVIDER: S-EPMC4816045 | biostudies-literature | 2015 Jul-Aug
REPOSITORIES: biostudies-literature
Jeng Mark Y MY Ali Ibraheem I Ott Melanie M
Critical reviews in biochemistry and molecular biology 20150701 4
Over the past 15 years, protein acetylation has emerged as a globally important post-translational modification that fine-tunes major cellular processes in many life forms. This dynamic regulatory system is critical both for complex eukaryotic cells and for the viruses that infect them. HIV-1 accesses the host acetylation network by interacting with several key enzymes, thereby promoting infection at multiple steps during the viral life cycle. Inhibitors of host histone deacetylases and bromodom ...[more]