Ontology highlight
ABSTRACT:
SUBMITTER: Kim DY
PROVIDER: S-EPMC4816100 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Cell death and differentiation 20151016 12
Forkhead transcription factor family O (FoxO) maintains adult stem cell reserves by supporting their long-term proliferative potential. MicroRNAs (miRs) regulate neuronal stem/progenitor cell (NSPC) proliferation and differentiation during neural development by controlling the expression of a specific set of target genes. In the neurogenic subventricular zone, FoxO1 is specifically expressed in NSPCs and is no longer detected during the transition to neuroblast stage, forming an inverse correlat ...[more]