Ontology highlight
ABSTRACT:
SUBMITTER: Koski A
PROVIDER: S-EPMC4817914 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Koski Anniina A Bramante Simona S Kipar Anja A Oksanen Minna M Juhila Juuso J Vassilev Lotta L Joensuu Timo T Kanerva Anna A Hemminki Akseli A
Molecular therapy : the journal of the American Society of Gene Therapy 20150709 10
In clinical trials with oncolytic adenoviruses, there has been no mortality associated with treatment vectors. Likewise, in the Advanced Therapy Access Program (ATAP), where 290 patients were treated with 10 different viruses, no vector-related mortality was observed. However, as the patient population who received adenovirus treatments in ATAP represented heavily pretreated patients, often with very advanced disease, some patients died relatively soon after receiving their virus treatment manda ...[more]