Ontology highlight
ABSTRACT:
SUBMITTER: Slezak-Prochazka I
PROVIDER: S-EPMC4823043 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Slezak-Prochazka Izabella I Kluiver Joost J de Jong Debora D Smigielska-Czepiel Katarzyna K Kortman Gertrud G Winkle Melanie M Rutgers Bea B Koerts Jasper J Visser Lydia L Diepstra Arjan A Kroesen Bart-Jan BJ van den Berg Anke A
Oncotarget 20160101 3
Several studies have indicated an important role for miR-155 in the pathogenesis of B-cell lymphoma. Highly elevated levels of miR-155 were indeed observed in most B-cell lymphomas with the exception of Burkitt lymphoma (BL). However, the molecular mechanisms that underlie the oncogenic role of miR-155 in B-cell lymphoma are not well understood. To identify the miR-155 targets relevant for B-cell lymphoma, we performed RNA immunoprecipitation of Argonaute 2 in Hodgkin lymphoma (HL) cells upon mi ...[more]