Post-Mortem evaluation of amyloid-dopamine terminal positron emission tomography dementia classifications.
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ABSTRACT:
SUBMITTER: Albin RL
PROVIDER: S-EPMC4836870 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
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Post-Mortem evaluation of amyloid-dopamine terminal positron emission tomography dementia classifications.
Albin Roger L RL Fisher-Hubbard Amanda A Shanmugasundaram Krithika K Koeppe Robert A RA Burke James F JF Camelo-Piragua Sandra S Lieberman Andrew P AP Giordani Bruno B Frey Kirk A KA
Annals of neurology 20150825 5
Clinical classification of early dementia and mild cognitive impairment (MCI) is imprecise. We reported previously that molecular imaging classification of early dementia and MCI with dual amyloid and dopamine terminal positron emission tomography differs significantly from expert clinical classification. We now report pathological diagnoses in a substantial subset of our previously imaged subjects. Among 36 subjects coming to autopsy, imaging classifications and pathological diagnosis were conc ...[more]
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