Ontology highlight
ABSTRACT:
SUBMITTER: Thal DR
PROVIDER: S-EPMC6854805 | biostudies-literature | 2019 Nov
REPOSITORIES: biostudies-literature
Thal Dietmar Rudolf DR Ronisz Alicja A Tousseyn Thomas T Rijal Upadhaya Ajeet A Balakrishnan Karthikeyan K Vandenberghe Rik R Vandenbulcke Mathieu M von Arnim Christine A F CAF Otto Markus M Beach Thomas G TG Lilja Johan J Heurling Kerstin K Chakrabarty Aruna A Ismail Azzam A Buckley Christopher C Smith Adrian P L APL Kumar Sathish S Farrar Gill G Walter Jochen J
Acta neuropathologica communications 20191114 1
Alzheimer's disease (AD)-related amyloid β-peptide (Aβ) pathology in the form of amyloid plaques and cerebral amyloid angiopathy (CAA) spreads in its topographical distribution, increases in quantity, and undergoes qualitative changes in its composition of modified Aβ species throughout the pathogenesis of AD. It is not clear which of these aspects of Aβ pathology contribute to AD progression and to what extent amyloid positron emission tomography (PET) reflects each of these aspects. To address ...[more]