Ontology highlight
ABSTRACT:
SUBMITTER: Kurylowicz A
PROVIDER: S-EPMC4849028 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20160419 4
Most of the available non-invasive medical therapies for obesity are non-efficient in a long-term evaluation; therefore there is a constant need for new methods of treatment. Research on calorie restriction has led to the discovery of sirtuins (silent information regulators, SIRTs), enzymes regulating different cellular pathways that may constitute potential targets in the treatment of obesity. This review paper presents the role of SIRTs in the regulation of glucose and lipid metabolism as well ...[more]