Ontology highlight
ABSTRACT:
SUBMITTER: Buchheit KM
PROVIDER: S-EPMC4853506 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Buchheit Kathleen M KM Laidlaw Tanya M TM
Allergy, asthma & immunology research 20160701 4
Aspirin-exacerbated respiratory disease (AERD) is an adult-onset upper and lower airway disease consisting of eosinophilic nasal polyps, asthma, and respiratory reactions to cyclooxygenase 1 (COX-1) inhibitors. Management includes guideline-based treatment of asthma and sinus disease, avoidance of COX-1 inhibitors, and for some patients aspirin desensitization followed by high-dose aspirin therapy. Despite this, many patients have inadequately controlled symptoms and require multiple sinus surge ...[more]