Ontology highlight
ABSTRACT:
SUBMITTER: Ramachandran S
PROVIDER: S-EPMC4855302 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Cell 20160407 3
Every nucleosome across the genome must be disrupted and reformed when the replication fork passes, but how chromatin organization is re-established following replication is unknown. To address this problem, we have developed Mapping In vivo Nascent Chromatin with EdU and sequencing (MINCE-seq) to characterize the genome-wide location of nucleosomes and other chromatin proteins behind replication forks at high temporal and spatial resolution. We find that the characteristic chromatin landscape a ...[more]