Ontology highlight
ABSTRACT:
SUBMITTER: Koerber RT
PROVIDER: S-EPMC2760215 | biostudies-literature | 2009 Sep
REPOSITORIES: biostudies-literature
Koerber R Thomas RT Rhee Ho Sung HS Jiang Cizhong C Pugh B Franklin BF
Molecular cell 20090901 6
A canonical nucleosome architecture around promoters establishes the context in which proteins regulate gene expression. Whether gene regulatory proteins that interact with nucleosomes are selective for individual nucleosome positions across the genome is not known. Here, we examine on a genomic scale several protein-nucleosome interactions, including those that (1) bind histones (Bdf1/SWR1 and Srm1), (2) bind specific DNA sequences (Rap1 and Reb1), and (3) potentially collide with nucleosomes d ...[more]