Ontology highlight
ABSTRACT:
SUBMITTER: Wang M
PROVIDER: S-EPMC4858728 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Nature communications 20160505
Genome-wide association studies (GWASs) have identified multiple susceptibility loci for colorectal cancer, but much of heritability remains unexplained. To identify additional susceptibility loci for colorectal cancer, here we perform a GWAS in 1,023 cases and 1,306 controls and replicate the findings in seven independent samples from China, comprising 5,317 cases and 6,887 controls. We find a variant at 12p13.2 associated with colorectal cancer risk (rs2238126 in ETV6, P=2.67 × 10(-10)). We re ...[more]