Ontology highlight
ABSTRACT:
SUBMITTER: Jung KH
PROVIDER: S-EPMC4860085 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Jung Kwang Hwa KH McCarthy Ryan L RL Zhou Chong C Uprety Nadima N Barton Michelle Craig MC Beretta Laura L
Stem cells (Dayton, Ohio) 20160201 5
MicroRNA expression profiling in human liver progenitor cells following hepatocytic differentiation identified miR-122 and miR-194 as the microRNAs most strongly upregulated during hepatocytic differentiation of progenitor cells. MiR-194 was also highly upregulated following hepatocytic differentiation of human embryonic stem cells (hESCs). Overexpression of miR-194 in progenitor cells accelerated their differentiation into hepatocytes, as measured by morphological features such as canaliculi an ...[more]