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ABSTRACT:
SUBMITTER: Sigwalt D
PROVIDER: S-EPMC4861662 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Sigwalt David D Moncelet Damien D Falcinelli Shane S Mandadapu Vijaybabu V Zavalij Peter Y PY Day Anthony A Briken Volker V Isaacs Lyle L
ChemMedChem 20160315 9
Two acyclic cucurbit[n]uril (CB[n])-type molecular containers that differ in the length of the (CH2 )n linker (M2C2: n=2, M2C4: n=4) between their aromatic sidewalls and sulfonate solubilizing groups were prepared and studied. The inherent solubilities of M2C2 (68 mm) and M2C4 (196 mm) are higher than the analogue with a (CH2 )3 linker (M2, 14 mm) studied previously. (1) H NMR dilution experiments show that M2C2 and M2C4 do not self-associate in water, which enables their use as solubilizing exc ...[more]