Mathematical Models of Tuberculosis Reactivation and Relapse.
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ABSTRACT:
SUBMITTER: Wallis RS
PROVIDER: S-EPMC4869524 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Mathematical Models of Tuberculosis Reactivation and Relapse.
Frontiers in microbiology 20160517
The natural history of human infection with Mycobacterium tuberculosis (Mtb) is highly variable, as is the response to treatment of active tuberculosis. There is presently no direct means to identify individuals in whom Mtb infection has been eradicated, whether by a bactericidal immune response or sterilizing antimicrobial chemotherapy. Mathematical models can assist in such circumstances by measuring or predicting events that cannot be directly observed. The 3 models discussed in this review i ...[more]
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