Ontology highlight
ABSTRACT:
SUBMITTER: Woodworth MB
PROVIDER: S-EPMC4873759 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Woodworth Mollie B MB Greig Luciano C LC Liu Kevin X KX Ippolito Gregory C GC Tucker Haley O HO Macklis Jeffrey D JD
Cell reports 20160421 5
The molecular linkage between neocortical projection neuron subtype and area development, which enables the establishment of functional areas by projection neuron populations appropriate for specific sensory and motor functions, is poorly understood. Here, we report that Ctip1 controls precision of neocortical development by regulating subtype identity in deep-layer projection neurons. Ctip1 is expressed by postmitotic callosal and corticothalamic projection neurons but is excluded over embryoni ...[more]