Gene therapy for the treatment of heart failure: promise postponed.
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ABSTRACT:
SUBMITTER: Hulot JS
PROVIDER: S-EPMC4887702 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Publications
Gene therapy for the treatment of heart failure: promise postponed.
Hulot Jean-Sebastien JS Ishikawa Kiyotake K Hajjar Roger J RJ
European heart journal 20160227 21
Gene therapy has emerged as a powerful tool in targeting the molecular mechanisms implicated in heart failure. Refinements in vector technology, including the development of recombinant adeno-associated vectors, have allowed for safe, long-term, and efficient gene transfer to the myocardium. These advancements, coupled with evolving delivery techniques, have placed gene therapy as a viable therapeutic option for patients with heart failure. However, after much promise in early-phase clinical tri ...[more]
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