Ontology highlight
ABSTRACT:
SUBMITTER: Zheng LD
PROVIDER: S-EPMC4889851 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Zheng Louise D LD Linarelli Leah E LE Brooke Joseph J Smith Cayleen C Wall Sarah S SS Greenawald Mark H MH Seidel Richard W RW Estabrooks Paul A PA Almeida Fabio A FA Cheng Zhiyong Z
Oxidative medicine and cellular longevity 20160519
Type 2 diabetes (T2D) is characterized by mitochondrial derangement and oxidative stress. With no known cure for T2D, it is critical to identify mitochondrial biomarkers for early diagnosis of prediabetes and disease prevention. Here we examined 87 participants on the diagnosis power of fasting glucose (FG) and hemoglobin A1c levels and investigated their interactions with mitochondrial DNA methylation. FG and A1c led to discordant diagnostic results irrespective of increased body mass index (BM ...[more]