Ontology highlight
ABSTRACT:
SUBMITTER: Zhao L
PROVIDER: S-EPMC4891668 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Zhao Liangcai L Dong Minjian M Liao Shixian S Du Yao Y Zhou Qi Q Zheng Hong H Chen Minjiang M Ji Jiansong J Gao Hongchang H
Scientific reports 20160603
Renal fibrosis is one of the important pathways involved in end-stage renal failure. Investigating the metabolic changes in the progression of disease may enhance the understanding of its pathogenesis and therapeutic information. In this study, (1)H-nuclear magnetic resonance (NMR)-based metabonomics was firstly used to screen the metabolic changes in urine and kidney tissues of renal interstitial fibrotic rats induced by unilateral ureteral obstruction (UUO), at 7, 14, 21, and 28 days after ope ...[more]