Ontology highlight
ABSTRACT:
SUBMITTER: Gohil SV
PROVIDER: S-EPMC4894319 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Gohil Shalini V SV Adams Douglas J DJ Maye Peter P Rowe David W DW Nair Lakshmi S LS
Journal of biomedical materials research. Part A 20140303 12
The aim of the study is use of transgenic fluorescent protein reporter mouse models to understand the cellular processes in recombinant human bone morphogenetic protein-2 (rhBMP-2) mediated bone formation. Bilateral parietal calvarial bone defects in Col3.6Topaz transgenic fluorescent osteoblast reporter mouse were used to understand the bone formation in the presence and absence of rhBMP2 and/or Col3.6Cyan bone marrow derived stromal cells (BMSCs), using collagen-hydroxyapatite matrix (Healos) ...[more]