Ontology highlight
ABSTRACT:
SUBMITTER: Blanchard GB
PROVIDER: S-EPMC4894466 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Blanchard Guy B GB Kabla Alexandre J AJ Schultz Nora L NL Butler Lucy C LC Sanson Benedicte B Gorfinkiel Nicole N Mahadevan L L Adams Richard J RJ
Nature methods 20090503 6
The dynamic reshaping of tissues during morphogenesis results from a combination of individual cell behaviors and collective cell rearrangements. However, a comprehensive framework to unambiguously measure and link cell behavior to tissue morphogenesis is lacking. Here we introduce such a kinematic framework, bridging cell and tissue behaviors at an intermediate, mesoscopic, level of cell clusters or domains. By measuring domain deformation in terms of the relative motion of cell positions and t ...[more]