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Pathologic aspects of skull base tumors.


ABSTRACT: Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most common malignancies are presented, along with a short histopathologic description. For some entities, an immunohistochemical profile is also given that should be helpful in proper diagnosis. As many pathologic diagnoses nowadays also include genetic studies, the most common genetic abnormalities in skull base tumors are presented.

SUBMITTER: Marszalek A 

PROVIDER: S-EPMC4899430 | biostudies-literature | 2016 Jul-Aug

REPOSITORIES: biostudies-literature

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Pathologic aspects of skull base tumors.

Marszałek Andrzej A   Szylberg Łukasz Ł   Wiśniewski Sławomir S  

Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology 20160403 4


Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most common malignancies are presented, along with a short histopathologic description. For some entities, an immunohistochemical profile is also given that should be helpful in proper diagnosis. As many pathologic diagnoses nowadays also include gen  ...[more]

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