Ontology highlight
ABSTRACT:
SUBMITTER: Bai DC
PROVIDER: S-EPMC4906412 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Nature communications 20160610
The palladium-catalysed allylic substitution reaction is one of the most important reactions in transition-metal catalysis and has been well-studied in the past decades. Most of the reactions proceed through an outer-sphere mechanism, affording linear products when monosubstituted allyl reagents are used. Here, we report an efficient Palladium-catalysed protocol for reactions of β-substituted ketones with monosubstituted allyl substrates, simply by using N-heterocyclic carbene as ligand, leading ...[more]