Ontology highlight
ABSTRACT:
SUBMITTER: Deller RC
PROVIDER: S-EPMC4918798 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Deller Robert C RC Pessin Jeffrey E JE Vatish Manu M Mitchell Daniel A DA Gibson Matthew I MI
Biomaterials science 20160506 7
Cell cryopreservation is an essential tool in modern biotechnology and medicine. The ability to freeze, store and distribute materials underpins basic cell biology and enables storage of donor cells needed for transplantation and regenerative medicine. However, many cell types do not survive freezing and the current state-of-the-art involves the addition of significant amounts of organic solvents as cryoprotectants, which themselves can be cytotoxic, or simply interfere with assays. A key cause ...[more]