Ontology highlight
ABSTRACT:
SUBMITTER: Sakhtah H
PROVIDER: S-EPMC4922186 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Sakhtah Hassan H Koyama Leslie L Zhang Yihan Y Morales Diana K DK Fields Blanche L BL Price-Whelan Alexa A Hogan Deborah A DA Shepard Kenneth K Dietrich Lars E P LE
Proceedings of the National Academy of Sciences of the United States of America 20160606 25
Redox-cycling compounds, including endogenously produced phenazine antibiotics, induce expression of the efflux pump MexGHI-OpmD in the opportunistic pathogen Pseudomonas aeruginosa Previous studies of P. aeruginosa virulence, physiology, and biofilm development have focused on the blue phenazine pyocyanin and the yellow phenazine-1-carboxylic acid (PCA). In P. aeruginosa phenazine biosynthesis, conversion of PCA to pyocyanin is presumed to proceed through the intermediate 5-methylphenazine-1-ca ...[more]