Ontology highlight
ABSTRACT:
SUBMITTER: Li J
PROVIDER: S-EPMC4929289 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Li Jing J Dong Xiaojing X Zhao Lei L Wang Xiao X Wang Yan Y Yang Xi X Wang Hong H Zhao Weiming W
Journal of cellular and molecular medicine 20160329 7
Natural killer (NK) cell is an important component in innate immunity, playing a critical role in bridging innate and adaptive immunity by modulating the function of other immune cells including T cells. In this study, we focused on the role of NK cells in regulating Th1/Treg and Th17/Treg balance during chlamydial lung infection. We found that NK cell-depleted mice showed decreased Th1 and Th17 cells, which was correlated with reduced interferon-γ, interleukin (IL)-12, IL-17 and IL-22 productio ...[more]