Ontology highlight
ABSTRACT:
SUBMITTER: Tousley A
PROVIDER: S-EPMC4942721 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Journal of Huntington's disease 20160601 2
Induced pluripotent stem cells (iPSCs) derived from controls and patients can act as a starting point for in vitro differentiation into human brain cells for discovery of novel targets and treatments for human disease without the same ethical limitations posed by embryonic stem cells. Numerous groups have successfully produced and characterized Huntington's disease (HD) iPSCs with different CAG repeat lengths, including cells from patients with one or two HD alleles. HD iPSCs and the neural cell ...[more]