Ontology highlight
ABSTRACT:
SUBMITTER: Memczak H
PROVIDER: S-EPMC4944999 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Memczak Henry H Lauster Daniel D Kar Parimal P Di Lella Santiago S Volkmer Rudolf R Knecht Volker V Herrmann Andreas A Ehrentreich-Förster Eva E Bier Frank F FF Stöcklein Walter F M WF
PloS one 20160714 7
Antibodies against spike proteins of influenza are used as a tool for characterization of viruses and therapeutic approaches. However, development, production and quality control of antibodies is expensive and time consuming. To circumvent these difficulties, three peptides were derived from complementarity determining regions of an antibody heavy chain against influenza A spike glycoprotein. Their binding properties were studied experimentally, and by molecular dynamics simulations. Two peptide ...[more]