Ontology highlight
ABSTRACT:
SUBMITTER: Stoesser N
PROVIDER: S-EPMC4958194 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Stoesser Nicole N Sheppard Anna E AE Peirano Gisele G Sebra Robert P RP Lynch Tarah T Anson Luke W LW Kasarskis Andrew A Motyl Mary R MR Crook Derrick W DW Pitout Johann D JD
Antimicrobial agents and chemotherapy 20160722 8
The blaIMP-14 carbapenem resistance gene has largely previously been observed in Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and sequencing of carbapenem-resistant Escherichia coli, we identified a sequence type 131 strain harboring blaIMP-14 within a class 1 integron, itself nested within an ∼54-kb multidrug resistance region on an epidemic IncA/C2 plasmid. The emergence of blaIMP-14 in this context in the ST131 lineage is of potential clinical concern. ...[more]