Ontology highlight
ABSTRACT:
SUBMITTER: Chapman RM
PROVIDER: S-EPMC4959798 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Chapman Robert M RM Gardner Margaret N MN Mapstone Mark M Klorman Rafael R Porsteinsson Anton P AP Dupree Haley M HM Antonsdottir Inga M IM Kamalyan Lily L
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20160316 6
<h4>Objective</h4>To determine how aging and dementia affect the brain's initial storing of task-relevant and irrelevant information in short-term memory.<h4>Methods</h4>We used brain Event-Related Potentials (ERPs) to measure short-term memory storage (ERP component C250) in 36 Young Adults, 36 Normal Elderly, and 36 early-stage AD subjects. Participants performed the Number-Letter task, a cognitive paradigm requiring memory storage of a first relevant stimulus to compare it with a second stimu ...[more]