Ontology highlight
ABSTRACT:
SUBMITTER: Ciesielski GL
PROVIDER: S-EPMC4964852 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Ciesielski G L GL Oliveira M T MT Kaguni L S LS
The Enzymes 20160509
Recent advances in the field of mitochondrial DNA (mtDNA) replication highlight the diversity of both the mechanisms utilized and the structural and functional organization of the proteins at mtDNA replication fork, despite the relative simplicity of the animal mtDNA genome. DNA polymerase γ, mtDNA helicase and mitochondrial single-stranded DNA-binding protein-the key replisome proteins, have evolved distinct structural features and biochemical properties. These appear to be correlated with mtDN ...[more]