Ontology highlight
ABSTRACT:
SUBMITTER: Ventress JK
PROVIDER: S-EPMC4965146 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
PloS one 20160728 7
Staphylococcus aureus is one of the primary causative agents of skin and wound infections. As bacterial adherence is essential for infection, blocking this step can reduce invasion of host tissues by pathogens. An anti-adhesion therapy, based on a host membrane protein family, the tetraspanins, has been developed that can inhibit the adhesion of S. aureus to human cells. Synthetic peptides derived from a keratinocyte-expressed tetraspanin, CD9, were tested for anti-adhesive properties and at low ...[more]