Ontology highlight
ABSTRACT:
SUBMITTER: Sun X
PROVIDER: S-EPMC4968118 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Sun Xuan X Suo Jian J Yan Jun J
World journal of gastroenterology 20160701 28
Human colorectal cancer (CRC) is the third most commonly diagnosed malignancies and the prognosis for patients with recurrent or metastatic disease is extremely poor. Although new chemotherapeutic regimen improves survival rates, therapy with better efficacy and less adverse effects is drastically needed. Immunotherapy has been investigated in human CRC for decades with limited success. However, recent developments of immunotherapy, particularly immune checkpoint inhibitor therapy, have achieved ...[more]