Ontology highlight
ABSTRACT:
SUBMITTER: Serrao EM
PROVIDER: S-EPMC4973679 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
NMR in biomedicine 20160616 8
Imaging of the metabolism of hyperpolarized [1-(13) C]pyruvate has shown considerable promise in preclinical studies in oncology, particularly for the assessment of early treatment response. The repeatability of measurements of (13) C label exchange between pyruvate and lactate was determined in a murine lymphoma model in fasted and non-fasted animals. The fasted state showed lower intra-individual variability, although the [1-(13) C]lactate/[1-(13) C]pyruvate signal ratio was significantly grea ...[more]