Ontology highlight
ABSTRACT:
SUBMITTER: Goto Y
PROVIDER: S-EPMC4976334 | biostudies-literature | 2016 Aug
REPOSITORIES: biostudies-literature
Goto Yusuke Y Yanagi Itaru I Matsui Kazuma K Yokoi Takahide T Takeda Ken-Ichi K
Scientific reports 20160808
The practical use of solid-state nanopores for DNA sequencing requires easy fabrication of the nanopores, reduction of the DNA movement speed and reduction of the ionic current noise. Here, we report an integrated nanopore platform with a nanobead structure that decelerates DNA movement and an insulating polyimide layer that reduces noise. To enable rapid nanopore fabrication, we introduced a controlled dielectric breakdown (CDB) process into our system. DNA translocation experiments revealed th ...[more]