Ontology highlight
ABSTRACT:
SUBMITTER: Morstein J
PROVIDER: S-EPMC4976628 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20160523 28
A method for the trifluoromethylation of arylsilanes is reported. The reaction proceeds with [(phen)CuCF3 ] as the CF3 source under mild, oxidative conditions with high functional-group compatibility. This transformation complements prior trifluoromethylation of arenes in several ways. Most important, this method converts arylsilanes formed by the silylation of aryl C-H bonds to trifluoromethylarenes, thereby allowing the conversion of arenes to trifluoromethylarenes. The unique capabilities of ...[more]