Ontology highlight
ABSTRACT:
SUBMITTER: Marchadier E
PROVIDER: S-EPMC4987107 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Genome biology and evolution 20160714 7
To progress our understanding of molecular evolution from a collection of well-studied genes toward the level of the cell, we must consider whole systems. Here, we reveal the evolution of an important intracellular signaling system. The calcium-signaling toolkit is made up of different multidomain proteins that have undergone duplication, recombination, sequence divergence, and selection. The picture of evolution, considering the repertoire of proteins in the toolkit of both extant organisms and ...[more]