Ontology highlight
ABSTRACT:
SUBMITTER: Chakraborty B
PROVIDER: S-EPMC4988949 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Chakraborty Bibhas B Ghosh Palash P Moodie Erica E M EE Rush A John AJ
Biometrics 20160217 3
A dynamic treatment regimen consists of decision rules that recommend how to individualize treatment to patients based on available treatment and covariate history. In many scientific domains, these decision rules are shared across stages of intervention. As an illustrative example, we discuss STAR*D, a multistage randomized clinical trial for treating major depression. Estimating these shared decision rules often amounts to estimating parameters indexing the decision rules that are shared acros ...[more]