Ontology highlight
ABSTRACT:
SUBMITTER: Koopman JJ
PROVIDER: S-EPMC4993336 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Koopman Jacob J E JJ Pijpe Jeroen J Böhringer Stefan S van Bodegom David D Eriksson Ulrika K UK Sanchez-Faddeev Hernando H Ziem Juventus B JB Zwaan Bas B Slagboom P Eline PE de Knijff Peter P Westendorp Rudi G J RG
Aging 20160701 7
Human survival probability and fertility decline strongly with age. These life history traits have been shaped by evolution. However, research has failed to uncover a consistent genetic determination of variation in survival and fertility. As an explanation, such genetic determinants have been selected in adverse environments, in which humans have lived during most of their history, but are almost exclusively studied in populations in modern affluent environments. Here, we present a large-scale ...[more]