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Diverse N-Heterocyclic Ring Systems via Aza-Heck Cyclizations of N-(Pentafluorobenzoyloxy)sulfonamides.

ABSTRACT: Aza-Heck cyclizations initiated by oxidative addition of Pd(0) -catalysts into the N-O bond of N-(pentafluoro-benzoyloxy)sulfonamides are described. These studies, which encompass only the second class of aza-Heck reaction developed to date, provide direct access to diverse N-heterocyclic ring systems.

SUBMITTER: Hazelden IR

PROVIDER: S-EPMC5010782 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature

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Diverse N-Heterocyclic Ring Systems via Aza-Heck Cyclizations of N-(Pentafluorobenzoyloxy)sulfonamides.

Hazelden Ian R IR Ma Xiaofeng X Langer Thomas T Bower John F JF

Angewandte Chemie (International ed. in English) 20160727 37

Aza-Heck cyclizations initiated by oxidative addition of Pd(0) -catalysts into the N-O bond of N-(pentafluoro-benzoyloxy)sulfonamides are described. These studies, which encompass only the second class of aza-Heck reaction developed to date, provide direct access to diverse N-heterocyclic ring systems. ...[more]

PMID: 27460965

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