Ontology highlight
ABSTRACT:
SUBMITTER: Hiranuma K
PROVIDER: S-EPMC5011489 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
FEBS open bio 20160713 9
The extracellular matrix protein nephronectin (Npnt), also called POEM, is considered to play critical roles as an adhesion molecule in development and functions of various tissues, such as the kidneys, liver, and bone. In the present study, we examined the molecular mechanism of Npnt gene expression and found that vitamin D3 (1α,25-dihydroxyvitamin D3,VD 3) strongly enhanced Npnt mRNA expression in MC3T3-E1 cells from a mouse osteoblastic cell line. The VD 3-induced increase in Npnt expression ...[more]