Ontology highlight
ABSTRACT:
SUBMITTER: Xia Y
PROVIDER: S-EPMC5013447 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Scientific reports 20160907
Dectin-1, a classical pattern-recognition receptor, was now identified as an important regulator in immune homeostasis and cancer immunity through its extensive ligands binding functions and subsequent cytokines production. The aim of this study was to assess the clinical significance of dectin-1 expression in 290 patients with clear cell renal cell carcinoma (ccRCC) through immunohistochemistry on tissue microarrays. We found that dectin-1 was predominantly expressed on ccRCC cells, in accordan ...[more]