Ontology highlight
ABSTRACT:
SUBMITTER: Costa TRD
PROVIDER: S-EPMC5018250 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Costa Tiago R D TRD Ilangovan Aravindan A Ukleja Marta M Redzej Adam A Santini Joanne M JM Smith Terry K TK Egelman Edward H EH Waksman Gabriel G
Cell 20160901 6
Conjugative pili are widespread bacterial appendages that play important roles in horizontal gene transfer, in spread of antibiotic resistance genes, and as sites of phage attachment. Among conjugative pili, the F "sex" pilus encoded by the F plasmid is the best functionally characterized, and it is also historically the most important, as the discovery of F-plasmid-mediated conjugation ushered in the era of molecular biology and genetics. Yet, its structure is unknown. Here, we present atomic m ...[more]