From Wasting to Obesity: The Contribution of Nutritional Status to Immune Activation in HIV Infection.
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ABSTRACT:
SUBMITTER: Koethe JR
PROVIDER: S-EPMC5021242 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
From Wasting to Obesity: The Contribution of Nutritional Status to Immune Activation in HIV Infection.
Koethe John R JR Heimburger Douglas C DC PrayGod George G Filteau Suzanne S
The Journal of infectious diseases 20161001
The impact of human immunodeficiency virus (HIV) infection on innate and adaptive immune activation occurs in the context of host factors, which serve to augment or dampen the physiologic response to the virus. Independent of HIV infection, nutritional status, particularly body composition, affects innate immune activation through a variety of conditions, including reduced mucosal barrier defenses and microbiome dysbiosis in malnutrition and the proinflammatory contribution of adipocytes and str ...[more]
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