Ontology highlight
ABSTRACT:
SUBMITTER: Jin SM
PROVIDER: S-EPMC5024060 | biostudies-literature | 2015 Jun
REPOSITORIES: biostudies-literature
Diabetes, obesity & metabolism 20150208 6
We aimed to compare the efficacy and safety of lobeglitazone and pioglitazone as add-ons to metformin in patients with type 2 diabetes. Patients who were inadequately controlled by metformin were randomized and treated once daily with either lobeglitazone (0.5 mg, n = 128) or pioglitazone (15 mg, n = 125) for 24 weeks, with a 28-week extension trial of lobeglitazone treatment in patients who consented. The primary endpoint was the change in glycated haemoglobin (HbA1c) concentration from baselin ...[more]