Ontology highlight
ABSTRACT:
SUBMITTER: Pinto R
PROVIDER: S-EPMC5041894 | biostudies-literature | 2016 May
REPOSITORIES: biostudies-literature
Pinto Rosamaria R De Summa Simona S Strippoli Sabino S Pilato Brunella B Azzariti Amalia A Guida Gabriella G Guida Michele M Tommasi Stefania S
Oncotarget 20160501 18
Metastatic melanoma (MM) is a highly aggressive cancer with a median overall survival of 6-9 months, notwithstanding the numerous efforts in development of new therapeutic approaches. To this aim we tested the clinical applicability of the Ion Torrent Personal Genome Machine to simultaneously screen MM patients in order to individuate new or already known SNPs and mutations able to predict the duration of response to BRAF inhibitors. An Ampliseq Custom Panel, including 11 crucial full length gen ...[more]