Ontology highlight
ABSTRACT:
SUBMITTER: Szameit K
PROVIDER: S-EPMC5056769 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Szameit Kristina K Berg Katharina K Kruspe Sven S Valentini Erica E Magbanua Eileen E Kwiatkowski Marcel M Chauvot de Beauchêne Isaure I Krichel Boris B Schamoni Kira K Uetrecht Charlotte C Svergun Dmitri I DI Schlüter Hartmut H Zacharias Martin M Hahn Ulrich U
RNA biology 20160729 10
G-quadruplexes have recently moved into focus of research in nucleic acids, thereby evolving in scientific significance from exceptional secondary structure motifs to complex modulators of gene regulation. Aptamers (nucleic acid based ligands with recognition properties for a specific target) that form Gquadruplexes may have particular potential for therapeutic applications as they combine the characteristics of specific targeting and Gquadruplex mediated stability and regulation. We have invest ...[more]