Ontology highlight
ABSTRACT:
SUBMITTER: Bing T
PROVIDER: S-EPMC5684193 | biostudies-literature | 2017 Nov
REPOSITORIES: biostudies-literature
Bing Tao T Zheng Wei W Zhang Xin X Shen Luyao L Liu Xiangjun X Wang Fuyi F Cui Jie J Cao Zehui Z Shangguan Dihua D
Scientific reports 20171113 1
Apart from the canonical Watson-Crick duplex, nucleic acids can often form other structures, e.g. G-quadruplex and triplex. These structures give nucleic acid additional functions besides coding for genetic information. Aptamers are one type of functional nucleic acids that bind to specific targets with high selectivity and affinity by folding into special tertiary structures. Despite the fact that numerous aptamers have been reported, only a few different types of aptamer structures are identif ...[more]