Ontology highlight
ABSTRACT:
SUBMITTER: Haga K
PROVIDER: S-EPMC5068309 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Haga Kei K Fujimoto Akira A Takai-Todaka Reiko R Miki Motohiro M Doan Yen Hai YH Murakami Kosuke K Yokoyama Masaru M Murata Kazuyoshi K Nakanishi Akira A Katayama Kazuhiko K
Proceedings of the National Academy of Sciences of the United States of America 20160928 41
Norovirus is the leading cause of acute gastroenteritis worldwide. Since the discovery of human norovirus (HuNoV), an efficient and reproducible norovirus replication system has not been established in cultured cells. Although limited amounts of virus particles can be produced when the HuNoV genome is directly transfected into cells, the HuNoV cycle of infection has not been successfully reproduced in any currently available cell-culture system. Those results imply that the identification of a f ...[more]